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KMID : 0387919950060020204
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Korean Journal of Cytopathology
1995 Volume.6 No. 2 p.204 ~ p.208
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Cytologic Features of Endodermal Sinus Tumor of Ovary in the Ascitic Fluid -Report of A Case-
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Abstract
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The cytologic findings of endodermal sinus tumor of the ovary are reported. The cytologic preperations were obtained from ascitic specimens. The findings on Papanicolaou-stained smears included a clean background and
poorly
preserved atypical cells
loosely arranged in irregular or papillary groups. At high magnification, the cells had il-defined and microvacuolated cytoplasms. with an increased nuclear-cytoplasmic ratio and prominent nucleoli. Hyaline globules characteristic of
the
alpha-fetoprotein (AFP)-synthesizing cells of endodermal sinus tumor were observed within the cells with periodiec-acid-Schiff(PAS) stain. The presence of PAS-positive hyaline globules can be regarded, therefore,
as
a
diagnostic clue to endodermal sinus tumor in an appropriate clinical setting and in the presence of AFP production. The cytologic findings in a cell block is important, in addition to smears, to obtain more diagnostic clues. A
preliminary cytomorphologic diagnosis of this highly malignant tumor is valuable as a guide in planning further immunocytochemical and serologic studies.
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KEYWORD
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